We love to modify DNA
Genome Editing Technologies
Scientists can precisely modify DNA in living cells and organisms, unlocking possibilities once thought impossible. These breakthroughs are the result of decades of relentless innovation in genetic engineering.
To truly revolutionize medicine and science, genome-editing technologies must be faster, more precise, and adaptable. Our mission is to build, refine, and optimize the next generation of these tools—pushing their boundaries to unlock new discoveries, cure diseases, and reshape the future of biotechnology
Protein Engineering & Directed Evolution
The power to edit genomes is transforming science and medicine—but can we push the boundaries even further? Are our current tools precise, efficient, and safe enough to truly revolutionize healthcare?
Genome-editing tools, incredible as they are, weren’t originally designed for precision medicine. They were discovered in nature and adapted for our needs, but they still lack key features necessary for their full potential in therapeutic applications.
That’s where we come in. Our lab is pioneering protein engineering and directed evolution to reimagine genome-editing tools from the ground up. By enhancing specificity, expanding targetability, and boosting robustness, we’re pushing these technologies beyond their natural limits. Our goal? To create next-generation genome-editing systems that are safer, more effective, and capable of treating an even wider range of genetic disorders.
The future of medicine is not just about using existing tools—it’s about creating better ones.
Molecular Medicines
Pioneering the Future of Medicine
Our research group aims to bridge the gap between the potential of genome editing technologies and their practical application in treating human diseases. We focus on unlocking their full therapeutic potential, making genome editing a reliable treatment for a broad range of genetic disorders. Located at the prestigious Heidelberg University, our team collaborates with leading laboratories to harness innovative tools for creating disease models and developing preclinical strategies to correct harmful genetic sequences.
